The rail route from Brussels to Antwerpen is a key connection between Belgium's capital and one of its major cities. The journey takes approximately 45 minutes, with trains operating frequently throughout the day, making this one of the best ways to travel between these two locations. Brussels, known for its historical architecture and rich cultural heritage, provides an interesting contrast to Antwerpen, celebrated for its diamond district and vibrant arts scene. On this page, you’ll find all the necessary details for planning your Brussels to Antwerpen trip, including schedules, ticket options, and frequently asked questions regarding this rail journey.