Discover the Charm and Convenience of the Avignon to Lyon Route. Traveling from Avignon to Lyon is a delightful journey made possible by France's efficient TGV high-speed train network. Covering around 230 kilometers, this route not only links two of France's most beautiful cities but does so with exceptional comfort and speed. The journey typically takes about 1.5 to 2 hours, making it a perfect choice for both leisure and business travelers. With numerous daily departures, the Avignon to Lyon train schedule is crafted to accommodate a variety of travel plans, ensuring an enjoyable and hassle-free experience.