The train route from Lille to Avignon connects the northern city of Lille, known for its rich cultural heritage and Flemish architecture, to Avignon in the south, famous for the historic Palais des Papes and the annual theatre festival. This journey typically involves a change in Paris, allowing travelers to explore another iconic French city briefly. The total travel time ranges from approximately 5 to 6 hours, depending on the connections chosen and train schedules. On this page, you will find crucial information for planning your Lille to Avignon trip, including available trains, ticket prices, and frequently asked questions about this rail journey.