The train route from Nantes to Lyon is a vital connection between these two significant French cities. The journey typically takes around 5 to 6 hours, with multiple services available throughout the day, including high-speed trains. Nantes, located on the Loire River, is known for its rich maritime history and cultural attractions, while Lyon, recognized for its historical architecture and culinary excellence, offers a different perspective of French life. This guide will provide all the necessary details for your Nantes to Lyon travel, such as departure times, ticket types, and answers to frequently asked questions regarding this important rail route.