Exploring Karlsruhe’s Train Stations. Karlsruhe boasts several key train stations that act as crucial hubs for both national and regional travel. The main station, Karlsruhe Hauptbahnhof, provides comprehensive services, including high-speed and international routes. Other important stations like Karlsruhe-Durlach specialize in regional connections, while Mühlburg Station caters to local travel needs. Each station is equipped with modern amenities to ensure a smooth journey, including customer service centers.