The Duisburg to Frankfurt (Main) route is a key rail connection in Germany, linking the Ruhr area's industrial hub with one of the country's financial centers. The journey typically takes around 1.5 to 2 hours, with various train options available, including Intercity Express (ICE) and Regional trains. Duisburg offers visitors a blend of industrial heritage and cultural attractions, while Frankfurt (Main) is renowned for its skyline and financial district. This page provides detailed information on train schedules, ticket choices, and frequently asked questions related to the Duisburg to Frankfurt (Main) travel route.