Traveling from Yatsushiro to Kobe can be done primarily by taking the Shinkansen services, specifically the Sakura and Mizuho trains. The Sakura Shinkansen operates at speeds up to 240 km/h (149 mph) and takes approximately 3 hours to traverse this journey, while making a few stops in between such as Kumamoto and Himeji. The Mizuho service, which is the fastest option, reaches speeds of up to 285 km/h (177 mph) and can complete the trip in about 2 hours and 45 minutes, with fewer stops, catering especially to those wanting a swift travel experience.
Both train services provide ample amenities, including comfortable seating and onboard food purchasing options. While the Mizuho is best for speed-driven travelers, the Sakura provides a balance for those looking to experience more of the regional areas with a slightly longer travel time.