The Intercity-Express (ICE) provides a high-speed connection between Mannheim and Hannover, reaching speeds of up to 300 km/h. The journey takes approximately 3 hours, offering comfortable seating, onboard dining options, and Wi-Fi access. Another option is the Intercity (IC) train, which travels at a slightly lower speed, around 200 km/h, and takes about 4 hours on the same route, providing a more economical travel choice.