The route between Nagaoka and Takasaki is primarily served by the Joetsu Shinkansen, specifically the Toki and Tanigawa services. The Toki Shinkansen is the faster option, reaching speeds of up to 240 km/h (149 mph) and completing the journey in approximately 1 hour and 10 minutes with limited stops, such as at Nagano and Ueno. The Tanigawa Shinkansen, on the other hand, makes more frequent stops along the way and takes around 1 hour and 50 minutes to reach Takasaki.
Both services offer comfortable seating options, with Standard and Green Class available, allowing passengers to choose between economical or more spacious travel. Onboard amenities include reclining seats, power outlets, and dining options, ensuring a pleasant journey. For those prioritizing speed, the Toki Shinkansen is the most efficient choice, while the Tanigawa is suited for travelers who wish to explore additional stations.