On the Akçaamara to Diyarbakir route, the main train service is operated by the state-run Turkish State Railways (TCDD). The main train type serving this route is the regional express service, which provides direct connections between the two cities. This service operates at speeds ranging from 80 km/h to 120 km/h (50 mph to 75 mph), taking approximately 6 to 7 hours for the complete journey, depending on the specific train schedule and possible stops along the way.
The regional express trains are generally equipped with comfortable seating, air conditioning, and basic onboard amenities, making for a tolerable trip. Unlike high-speed trains found in other countries, this route does not feature high-speed trains, reflecting the region's slower rail infrastructure. Passengers can enjoy scenic views of eastern Anatolia while traveling between Akçaamara and Diyarbakir.