G‑series high‑speed trains on the Shanghai to Liupanshuidong route provide Second, First, and Business Class seating, typically departing from Shanghai Hongqiao and arriving at Liupanshui East (Liupanshuidong). The fastest services run over the Shanghai–Kunming High‑Speed Railway, reaching 300–350 km/h (186–217 mph) across the eastern sections between Shanghai, Hangzhou East, Nanchang West, and Changsha South, then operating at about 200–250 km/h (124–155 mph) through the mountainous stretches of Guizhou between Guiyang North, Anshun West, and Liupanshuidong. With limited stops, end‑to‑end travel time is usually around 8 h 45 m to 9 h 30 m.
In comparison, other itineraries involve a change at Guiyang North or Anshun West and make more intermediate calls. These G or mixed G+D services generally take about 9.5–10.5 hours, with D‑series segments running up to 250 km/h (155 mph). Rolling stock on this corridor includes Fuxing (CR400) sets and Hexie EMUs such as CRH380/CRH2.
Onboard amenities include reserved seating (3+2 in Second Class, 2+2 in First Class, and 1+2 lie‑flat Business Class on selected trains), power outlets, and trolley/bistro service. Conventional overnight trains run to Liupanshui (main station) rather than Liupanshuidong at about 120–160 km/h (75–99 mph), taking 24–30 hours and requiring a local transfer to reach the East station.